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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STAT5B
All Species:
22.73
Human Site:
S427
Identified Species:
50
UniProt:
P51692
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51692
NP_036580.2
787
89866
S427
S
L
K
R
I
K
R
S
D
R
R
G
A
E
S
Chimpanzee
Pan troglodytes
XP_511502
782
89188
S422
S
L
K
R
I
K
R
S
D
R
R
G
A
E
S
Rhesus Macaque
Macaca mulatta
XP_001109557
794
90645
A427
S
L
K
R
I
K
R
A
D
R
R
G
A
E
S
Dog
Lupus familis
XP_548092
787
90122
S427
S
L
K
R
I
K
R
S
D
R
R
G
A
E
S
Cat
Felis silvestris
Mouse
Mus musculus
P42232
786
89984
S427
S
L
K
R
I
K
R
S
D
R
R
G
A
E
S
Rat
Rattus norvegicus
P52632
786
90205
S427
S
L
K
R
I
K
R
S
D
R
R
G
A
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6DV79
771
88152
G422
E
Q
R
C
G
N
G
G
R
A
N
C
D
A
S
Frog
Xenopus laevis
Q7ZXK3
766
87581
G422
E
Q
R
C
G
N
G
G
R
A
N
C
D
A
S
Zebra Danio
Brachydanio rerio
NP_919368
785
89465
S427
S
L
K
R
I
R
R
S
D
R
R
G
A
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24151
761
86396
A443
Q
L
K
K
I
K
R
A
E
K
K
G
T
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NAD6
706
80563
C363
T
V
H
G
S
Q
D
C
D
A
Q
V
A
I
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
92.6
97
N.A.
96.8
96.8
N.A.
N.A.
28.4
29.4
79
N.A.
31.2
N.A.
23.1
N.A.
Protein Similarity:
100
95.6
95
98.5
N.A.
98.2
98.3
N.A.
N.A.
49.2
49.2
88.4
N.A.
49.5
N.A.
42.6
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
100
100
N.A.
N.A.
6.6
6.6
93.3
N.A.
53.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
13.3
100
N.A.
86.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
19
0
28
0
0
73
19
0
% A
% Cys:
0
0
0
19
0
0
0
10
0
0
0
19
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
73
0
0
0
19
0
0
% D
% Glu:
19
0
0
0
0
0
0
0
10
0
0
0
0
73
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
19
0
19
19
0
0
0
73
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
73
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
73
10
0
64
0
0
0
10
10
0
0
0
0
% K
% Leu:
0
73
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
19
0
0
0
0
19
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
19
0
0
0
10
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
19
64
0
10
73
0
19
64
64
0
0
0
0
% R
% Ser:
64
0
0
0
10
0
0
55
0
0
0
0
0
0
91
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _